Carie R. Boychuk, PhD

Associate Professor of Pathobiology and Integrative Biomedical Sciences

College of Veterinary Medicine

Lab Website

laptop_windows Boychuk Lab

Areas of Expertise

Research summary

Our laboratory is dedicated to understanding how central circuits receive and process interoceptive signaling to generate autonomic motor output in the maintenance of homeostasis using cutting edge neurophysiological approaches. We provide unique insight into the integration of multiple physiological systems, with strong focuses in the context of cardiovascular and energy homeostatic regulation. We leverage novel mouse models to address fundamental mechanistic questions that we can scale up to translationally-relevant clinical problem.

Select publications

  • Wang, Y., Dow, KE. and Boychuk, CR. GABAA-δ receptors in vagal motor neurons play a role in the influence of high fat diet on cardiac function. iScience. 2025 Mar 22;28(4):112268.
  • Martins dos Santos, K, Saunders, SS., and Antunes, VR#, and Boychuk, CR#. Insulin activates parasympathetic hepatic-related neurons of the paraventricular nucleus of the hypothalamus through mTOR signaling. J Neurophysiol. 2025 Jan 1;133(1):320-332. doi: 10.1152/jn.00284.2024. Epub 2024 Dec 12.
  • Fekete, EM, Gomez, J, Ghobrial, M, Kaminski, K, Muskus, PC, Boychuk, CR, Guixa, AH, Vazirabad, I, Xie, M, Ganiyu, A, Golosova, D, Mathieu, NA, Wang, YB, Lu, K, Wackman, KK, Brozoski, DT, Mouradian, GC, Hodges, MR, Segar, JL, Grobe, JL, Sigmund, CD, and Nakagawa, P. Definitive Evidence for the Identification and Function of Renin-Expressing Cholinergic Neurons in the Nucleus Ambiguus. Hypertension. 2025 Feb;82(2):282-292. doi: 10.1161/HYPERTENSIONAHA.124.23740. Epub 2024 Dec 2.
  • Basu, T, Antonoudiou, P, Weiss, G, Coleman, E, David, J, Friedman, D, Laze, J, Strain, MM, Devinsky, O, Boychuk, CR, and Maguire, J. Hypothalamic–Pituitary–Adrenal Axis Dysfunction Elevates SUDEP Risk in a Sex-Specific Manner. eNeuro. 2024 Jul 10;11(7):ENEURO.0162-24.2024. doi: 10.1523/ENEURO.0162-24.2024. Print 2024 Jul.
  • Strain, MM*, Conley, NJ*, Kauffman, LS*, Espinoza, L, Fedorchak, S, Martinez, PC, Crook, MC, Jalil, M, Hodes, GE, Abbott, SBG, Guler, AD, Campbell, JN#. and Boychuk, CR#. iScience 27, 109137 March 15, 2024. https://doi.org/10.1016/j.isci.2024.109137.
  • Strain, MM*, Espinoza, L*, Fedorchak, S, Littlejohn, EL, Andrade, M, Toney, GM and Boychuk, CR. Early central cardiovagal dysfunction after high fat diet in a murine model. Sci Rep. 2023 Apr 21;13(1):6550. doi: 10.1038/s41598-023-32492-w.
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Lab staff

  • Sandy Saunders, PhD Postdoctoral Fellow
  • Yoko Wang, PhD, Postdoctoral Fellow
  • Kaylie Dow, BS, Graduate Student
  • Grace Bostic, Undergraduate Student